Shivani malik

Shivani malik

Company: Kura Oncology

Job title: Director - Translational Research


Conveying how Tipifarnib Suppresses KRAS G12C Inhibitor-Induced mTOR Reactivation Leading to Superior Antitumor Activity of the Combination 2:15 pm

Elucidating phase1/2 data for Tipifarnib, a potent, selective inhibitor of farnesyl transferase with alpelisib, a PIK3C alpha inhibitor as a potential therapy for patients with HRAS-overexpressing metastatic head and neck squamous cell carcinoma (The KURRENT-HN Trial) Showcasing how Tipifarnib is a farnesyl transferase inhibitor that blocks compensatory feedback reactivation through inhibition of adaptive mTOR signaling…Read more

day: Day Two Track B PM

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