How to Address Resistance Mechanisms to Increase Response Rates & Durability to Prevent Cancer Recurrence
Time: 9:01 am
day: Workshop D
RAS. Therefore, RAS-targeted drugs apply a strong selective force on cancer, leading to the
evolution of resistance.
Hence, understanding the mechanisms of resistance, as well as, pre-empting new ones for
different RAS therapies, and subsequently, developing strategies to counter them, is vital achieve
disease free survival of patients.
This workshop will:
- Review existing literature to compile an actionable list of resistance mechanisms
- Utilize previous learnings to predict resistance mechanisms for newer modalities to address challenges early on
- Develop strategies to deal with resistance, such as evolutionary medicine approaches, combination therapy, and many more