How to Address Resistance Mechanisms to Increase Response Rates & Durability to Prevent Cancer Recurrence

Time: 9:01 am
day: Workshop D


RAS. Therefore, RAS-targeted drugs apply a strong selective force on cancer, leading to the

evolution of resistance.

Hence, understanding the mechanisms of resistance, as well as, pre-empting new ones for

different RAS therapies, and subsequently, developing strategies to counter them, is vital achieve

disease free survival of patients.

This workshop will:

  • Review existing literature to compile an actionable list of resistance mechanisms
  • Utilize previous learnings to predict resistance mechanisms for newer modalities to address challenges early on
  • Develop strategies to deal with resistance, such as evolutionary medicine approaches, combination therapy, and many more