Chiara Ambrogio
Company: University of Turin
Job title: Associate Professor
Seminars:
Chair’s Closing Remarks & End of the 5th Annual RAS-Targeted Drug Development Summit 5:30 pm
day: Conference Day Two
Chair’s Opening Remarks 8:20 am
day: Conference Day Two
An Overview of the Resistance Mechanisms Against RAS-Targeted Drugs Beyond G12C 12:00 pm
Understanding the resistance profiles of different KRAS mutants to effectively target each mutation Differentiating resistance based on mechanism of action to devise the most effective treatment regimen and potential lines of treatment Combining the resistance profiles with histotype analysis of associated cancers for each mutation to create a holistic resistance profile Exploring feasibility of combination…Read more
day: Day One Track B AM
How to Address Resistance Mechanisms to Increase Response Rates & Durability to Prevent Cancer Recurrence 9:01 am
RAS. Therefore, RAS-targeted drugs apply a strong selective force on cancer, leading to the evolution of resistance. Hence, understanding the mechanisms of resistance, as well as, pre-empting new ones for different RAS therapies, and subsequently, developing strategies to counter them, is vital achieve disease free survival of patients. This workshop will: Review existing literature to…Read more
day: Workshop D