An Overview of the Resistance Mechanisms Against RAS-Targeted Drugs Beyond G12C
Time: 12:00 pm
day: Day One Track B AM
Details:
- Understanding the resistance profiles of different KRAS mutants to effectively target each mutation
- Differentiating resistance based on mechanism of action to devise the most effective treatment regimen and potential lines of treatment
- Combining the resistance profiles with histotype analysis of associated cancers for each mutation to create a holistic resistance profile
- Exploring feasibility of combination therapies based on validated molecular resistance mechanisms
