Chiara Ambrogio

Company: University of Turin

Job title: Associate Professor of Molecular Biology

Seminars:

Panel Discussion: Does Pan-RAS Hold the Future of Precision Medicine? Exploring Combination Potential & Targeting Novel Isoforms 9:00 am

What is the current scope and strides in developing pan-RAS inhibitors? What combination therapies should be deployed with pan-RAS and how can we inform this? What is the future of pan-RAS? Will it replace mutant-specific therapies?Read more

day: Day One

Debunking Safety & Efficacy Concerns Surrounding Targeting Wild Type KRAS to Induce Tumor Regression 8:30 am

Wild type KRAS continues to present a huge challenge in selectively targeting mutant variants implicated in cancer due to its structural similarity and essential cellular functions. Debate surrounds the feasibility and safety of directly targeting wild type KRAS, with concerns over potential off-target effects. Despite advances in structural and functional studies, these findings are yet…Read more

day: Workshop A