Translating Variant-Selective, Pan-RAS, and Combination Innovations into Robust, Potent Therapies Delivering Meaningful Clinical Benefit Across RAS-Driven Tumors
The 8th RAS-Targeted Drug Development Summit was the industry's only forum dedicated exclusively to translating RAS therapies from early discovery through clinical development. Bringing together leaders across biopharma, including Bristol Myers Squibb, Amgen, Revolution Medicines, Verastem, Incyte, Jacobio Pharmaceuticals and NCI, the meeting focused on the topics shaping the next era of RAS drug development: pan-RAS and pan-KRAS inhibition, RAS(ON) targeting, resistance mechanisms, pathway-based combinations, precision patient selection, and strategies to translate breakthrough clinical data into meaningful patient outcomes.
The summit brought together senior RAS-focused experts to share actionable insights on next-generation targeting strategies, innovative modalities, smarter combination design, and precision patient stratification, helping equip attendees to advance more effective RAS therapies for broader patient populations.
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As the field of RAS-targeted therapies continues to evolve rapidly, this meeting plays an important role in bringing together leaders across academia, biotech, and industry to exchange perspectives and align on the key scientific and clinical challenges ahead.
Ivana Sullivan, Clinical Research Medical Director, Amgen
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The meeting provides a platform to discuss an aspect of cancer biology that has been challenging to address. Finally, we are seeing promising advancements that have the potential to transform patient outcomes across multiple difficult to treat cancers.
Mani Mohindru, Chief Executive Officer, Cardiff Oncology
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Thought leaders in the field will convene into a focused forum aimed at removing current obstacles on the development and clinical uptake of RAS inhibitors, with the ultimate goal of improving durability of response and safety of RAS inhibitors, extending the life of patients further.
Federico Innocenti, Senior Director, Clinical Development, Solid Tumors, BeOne Medicines
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What You Missed
Accelerated More Durable Responses with Smarter RAS Combination Strategies
Delivered Next-Generation KRAS Therapies with Greater Efficacy & Tolerability
Expanded Patient Reach with Innovative Modalities Beyond Small Molecules
Broadened Therapeutic Impact Through Pan-KRAS & Pan-RAS Targeting
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