Jonathan Pachter

Jonathan Pachter

Company: Verastem. inc

Job title: Chief Scientific Officer


Vertical Inhibition of RAS, RAF & MEK: Enhancing Antitumor Efficacy of KRAS G12C & G12D Inhibitors with RAF/MEK Clamp Avutometinib (Vs-6766) 1:45 pm

Examining how Avutometinib, a RAF/MEK clamp, has established clinical activity and safety with oral intermittent dosing, providing a promising new therapy Showcasing how combination with G12C inhibitors yields a deeper pERK blockade for enhanced tumor regression in G12C inhibitor-naïve and -resistant models, indicating potential for improved patient outcomes Understanding how combination with KRAS G12D inhibitors…Read more

day: Day 2 Track A PM

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