Nick Larsen
Senior Director - Biophysics & Structural Biology Kestrel Therapeutics Inc
Seminars
Wednesday 17th September 2025
Roundtable Discussion: Comparing On vs. Off-State Approaches in the Targeting of RAS for Achieving More Durable & Efficacious Responses
2:00 pm
- How to achieve high specificity and affinity given the highly dynamic and flexible structures of the on- and off-states of RAS?
- Does targeting active or inactive states of RAS lead to more durable and tolerable treatments of cancer?
- Investigating the key challenges of targeting the active vs inactive states of RAS
