Improving Therapeutic Efficacy by Targeting the MAPK Pathway to Disrupt Tumor Growth & Reduce Oncogenesis
- How to target specific MAPK substrates that are critical for tumor growth without disrupting broader cellular functions
- How does targeting upstream and downstream regulators of RAS signaling enhance drug efficacy?
- Addressing how alternative signaling pathways, particularly the PI3K/AKT pathway, contribute to resistance against MAPK-targeted therapies