Translational Approach to KRAS Inhibitors & Mapping the Possible Mechanism of KRASi Resistance

  • The KRAS inhibitor Landscape: From Discovery to Clinical Hurdles
  • Establishment of Sotorasib and Adagrasib resistance PDX models. Leveraging MiniPDX and PDX Models for next generation KRASi screening
  • Decoding resistance mechanism through integrated bioinformatics