Frank McCormick
Company: UCSF
Job title: Professor & Leader of NCI RAS Initiative
Seminars:
The Journey Continues: Widening the Range of Targetable Indications to Expand the Therapeutic Breadth of RAS Inhibition 8:30 am
How to target rarer mutations beyond G12C such as G12V to broaden the types of cancers we can treat Advancing the understanding of histotypes and comparing various indications to inform drug discovery Combining mutational and histotype analysis to rationally design precision oncology therapiesRead more
day: Conference Day One
Chair’s Opening Remarks 8:20 am
day: Conference Day One
RAS 101: Understanding the RAS Pathway & Its Oncogenic Mutations to Improve Drug Discovery & Design 9:01 am
The RAS/MAPK pathway is an extremely important signalling cascade that plays a major role in driving oncogenesis. It stretches from receptors on the cell membrane to transcription factors in the nucleus and is naturally robust to prevent disruption. Hence, to effectively target RAS and its surrounding molecules for effective cancer therapy, it is important to…Read more
day: Workshop A