Camilo Velez-Vega

Camilo Velez-Vega

Company: Novartis AG

Job title: AD & Senior Principal Scientist


Membrane Composition & RAF [CRD]-Membrane Attachment are Driving Forces for KRAS4B Dimer Stability 2:30 pm

We performed all-atom molecular dynamics simulations of the KRAS4BGTP wild-type homodimer in the presence and absence of Raf [RBD/CRD] effectors on two model anionic lipid membranes The stability of the KRAS4B homodimer is enhanced on the membrane containing a high concentration of anionic lipids in the absence of Raf effectors This enhanced stability is also…Read more

day: Day Two Track D

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