Andrew Whale

Andrew Whale

Company: Immunocore Ltd

Job title: Associate Director, Pipeline Biology


Development of a Selective, Affinity-Enhanced T-Cell Receptor Bispecific Targeting KRASG12D Neoantigen Driven Cancers 5:00 pm

CD3xTCR bispecific proteins (bsp) redirect polyclonal T cells to target intracellular proteins in cancer; TCR bsp offer an attractive opportunity to target KRAS G12D neoantigen peptides presented by cell surface human leukocyte antigen We successfully engineered an off the shelf, soluble CD3xTCR bispecific molecule, IMC-KRAS G12D, that recognises a common shared KRAS G12D neoantigen peptide…Read more

day: Day One Track H

Targeted Delivery of Anti-RAS Therapeutics 12:00 pm

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day: Pre-Conference Day Track C

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