Kristen Bryant
Assistant Professor, Department of Pharmacology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Seminars
Tuesday 16th September 2025
Workshop B – Unravelling Resistance Mechanisms to Uncover Non-Invasive Strategies & Reliable Biomarkers for Accurate Understanding of RASTargeting Drugs
1:30 pm
As resistance mechanisms continue to limit the durability of RAS-targeted drugs, diving deep into these mechanisms and uncovering biomarker strategies is crucial for gaining deeper insights. Through liquid biopsy and ctDNA technologies you can discover effective biomarkers to help predict and identify resistance, enabling the development of more efficacious therapies and personalized treatment approaches.
This workshop will discuss:
- Exploring approaches to monitor and mitigate the multifaceted mechanisms underlying resistance to KRAS inhibitors for more durable treatment
- How to leverage ctDNA analysis for tracking emerging mutations and gaining insights into resistance mechanisms
- How to ensure biomarker reliability when working with heterogeneous tumors for more robust prediction and analysis
Thursday 18th September 2025
TRACK A: Drug Discovery & Preclinical Development
Moving Beyond Small Molecules to Find New Modalities for Effectively Treating RAS-Driven Cancers
